Journal paper



  1. Liu YC, Hung CS , Wu YW, Lee YC, Lin YH, Lin C, Lo MT, Chan CC, Ma HP, Ho YL, Chen CH, (2013) Influence of Non-Alcoholic Fatty Liver Disease on Autonomic Changes Evaluated by The Time Domain, Frequency Domain, and Symbolic Dynamics of Heart Rate Variability, PLoS ONE, 8(4): E61803
  2. Liu HM, Wong HF, Lee KW, Tu YK, Yeh YS, Chou CW, Wang YH, Chen YL, Lo YL, Hsieh TC, Wang YC, Lin TK, Lai DM, Chen WL, Tseng HM, Li CW. (2013) Taiwan Aneurysm Registry (TAR): Multivariate Analysis of 2-Month, 1-Year, and 2-Year Outcomes After Endovascular and Microsurgical Treatment of Ruptured Aneurysms, Interv Neuroradiol.
  3. Liu HM, Yang CY, Lee CW, Wang YH, Chen YF. (2013) Rapid, Sequential Bilateral Acute Carotid Blowout Syndrome, Neuroradiology
  4. Chung FH,  Lee Henry HC,  Lee HC (2013) Top: A Trend-of-Disease-Progression Procedure Works Well for Identifying Oncogenes from Multi-State Cohort Gene Expression Data for Human Colorectal Cancer. PLoS ONE, 8(6): e65683
  5. Chang HC, Lee PL, Lo MT, Wu YT, Wang KW, Lan GY. (2013) Inter-Trial Analysis of Post-Movement Beta Activities in EEG Signals Using Multivariate Empirical Mode Decomposition. IEEE Trans Neural Syst Rehabil Eng.
  6. Yeh CL, Lee PL, Chen WM, Chang CY, Wu YT, Lan GY. (2013) Improvement of Classification Accuracy in A Phase-Tagged Steady-State Visual Evoked Potential–Based Brain Computer Interface Using Multiclass Support Vector Machine. Biomed Eng Online
  7. Liu ME, Huang CC, Hwang JP, Yang AC, Tu PC, Yeh HL, Hong CJ, Liou YJ, Chen JF, Lin CP, Tsai SJ. (2013) Effect of Bcl-2 Rs956572 SNP on Regional Gray Matter Volumes and Cognitive Function in Elderly Males without Dementia. Age (Dordr)
  8. Tu PC, Su TP, Huang CC, Yang AC, Yeh HL, Hong CJ, Liou YJ, Liu ME, Lin CP, Tsai SJ. (2013) Interleukin-1 Beta C-511T Polymorphism Modulates Functional Connectivity of Anterior Midcingulate Cortex in Non-Demented Elderly Han Males. Brain Struct Funct.
  9. Ko FY, Yang AC, Tsai SJ, Zhou Y, Xu LM. (2013) Physiologic and Laboratory Correlates of Depression, Anxiety, and Poor Sleep in Liver Cirrhosis. BMC Gastroenterol.
  10. Tseng CM, Chen YT, Ou SM, Hsiao YH, Li SY, Wang SJ, Yang AC, Chen TJ, Perng DW. (2013) The Effect of Cold Temperature on Increased Exacerbation of Chronic Obstructive Pulmonary Disease: A Nationwide Study. PLoS One
  11. Liu ME, Huang CC, Yang AC, Tu PC, Yeh HL, Hong CJ, Chen JF, Liou YJ, Lin CP, Tsai SJ (2013) Effect of Bcl-2 Rs956572 Polymorphism on Age-Related Gray Matter Volume Changes. PLoS One.
  12. Yang AC, Tsai SJ  (2013) Complexity of Mental Illness: A New Research Dimension. Prog Neuropsychopharmacol Biol Psychiatry.
  13. Lu CF, Wang PS, Lao YL, Wu HM, Soong BW, Wu YT. (2013) Medullo-Ponto-Cerebellar White Matter Degeneration Altered Brain Network Organization and Cortical Morphology in Multiple System Atrophy, Brain Struct Funct.
  14. Lu CF, Soong BW, Wu HM, Teng S, Wang PS, Wu YT. (2013) Disrupted Cerebellar Connectivity Reduces Whole-Brain Network Efficiency in Multiple System Atrophy, Mov Disord
  15. Hu HH, Chen HY, Hung CI, Guo WY, Wu YT. (2012) Shape and Curvedness Analysis of Brain Morphology Using Human Fetal Magnetic Resonance Images in Utero. Brain Struct Funct
  16. Hu WP, Huang LY, Chen WY, (2013) Optimal Buffer Ph Value on The Detection of HAS by Using A Protein Chip Prepared by DNA-Directed Immobilization, Applied Mechanics and Materials
  17. Kuo TC, Lee PC, Tsai CW, Chen WY. (2013) Salt Bridge Exchange Binding Mechanism Between Streptavidin and Its DNA Aptamer Thermodynamics and Spectroscopic Evidences, J Mol Recognit
  18. Liang JF, Chen YT, Fuh JL, Li SY, Liu CJ, Chen TJ, Tang CH, Wang SJ. (2013) Cluster Headache Is Associated with An Increased Risk for Depression: A Nationwide Population-Based Cohort Study. Cephalalgia
  19. Yang FC, Chou KH, Fuh JL, Huang CC, Lirng JF, Lin YY, Lin CP, Wang SJ. (2013) Altered Gray Matter Volume in The Frontal Pain Modulation Network in Patients with Cluster Headache. Pain
  20. Chou CH, Doong ML, Fuh JL, Wu JC, Wang SJ. (2013) Queckenstedt’s Test Affects More Than Jugular Venous Congestion in Rat. PLoS One
  21. Hung CI, Liu CY, Wang SJ. (2013) Migraine Predicts Physical and Pain Symptoms Among Psychiatric Outpatients. J Headache Pain
  22. Wang SH, Chang YS, Liu CJ, Lai CC, Chen WS, Chen TJ, Wang SJ. (2013) Systemic Lupus Erythematosus Is Associated with A Higher Risk of Cervical But Not Trochanteric Hip Fracture: A Nationwide Population-Based Study. Arthritis Care Res (Hoboken)
  23. Chen SP, Chung YT, Liu TY, Wang YF, Fuh JL, Wang SJ. (2013) Oxidative Stress and Increased Formation of Vasoconstricting F2-Isoprostanes in Patients with Reversible Cerebral Vasoconstriction Syndrome. Free Radic Biol Med
  24. Wu CW W, Chao YP, (2012) Fundamental Concerns for Detecting Synchronized Brain Networks Using Resting-State Functional Magnetic Resonance Imaging, Journal of Neuroscience and Neuroengineering
  25. Liao YL, Wang PS, Lu CF, Hung CI, Li CT, Lin CP, Hsieh JC, Su TP, Wu YT, (2013) Cortical Shape and Curvedness Analysis of Structural Deficits in Remitting and Non-Remitting Depression, PLoS One
  26. Lu CF, Guo WY, Chang FC, Huang SR, Chou YC, Wu YT, (2013) Hemodynamic Segmentation of Brain Perfusion Images with Delay and Dispersion Effects Using An Expectation-Maximization Algorithm, PLoS One
  27. Guo SL, Han CT, Jung JL, Chen WJ, Mei JJ, Lee HC, Cheng YC, (2013) Cystatin C in Cerebrospinal Fluid Is Upregulated in Elderly Patients with Chronic Osteoarthritis Pain and Modulated via Matrix Metalloproteinase 9 Specific Pathway, Clin J Pain
  28. Lee CW, Yang CY, Chen YF, Huang A, Wang YH, Liu HM, (2013) CT Angiography Findings in Carotid Blowout Syndrome and Its Role As Prognostic Predictor of One-Year Survival, AJNR Am J Neuroradiol.
  29. Pittman-Polletta BR, Scheer FA, Butler MP, Shea SA, Hu K, (2013) The Role of The Circadian System in Fractal Neurophysiological Control, Biol Rev Camb Philos Soc.
  30. Hu K, Harper DG, Shea SA, Stopa EG, Scheer FA, (2013) Noninvasive Fractal Biomarker of Clock Neurotransmitter Disturbance in Humans with Dementia., Sci Rep
  31. Cao M, Guilleminault C, Lin C. (2013) Central Sleep Apnea: Effects on Stroke Volume in Heart Failure, Am J Respir Crit Care Med
  32. Yeh JR, Peng CK, Lo MT, Yeh CH, Chen SC, Wang CY, Lee PL, Kang JH, (2013) Investigating The Interaction Between Heart Rate Variability and Sleep EEG Using Nonlinear Algorithms, J Neurosci Methods
  33. Yang AC, Wang SJ, Lai KL, Tsai CF, Yang CH, Hwang JP, Lo MT, Huang NE, Peng CK, Fuh JL. (2013) Cognitive and Neuropsychiatric Correlates of EEG Dynamic Complexity in Patients with Alzheimer’s Disease, Prog Neuropsychopharmacol Biol Psychiatry.
  34. Lo MT, Lin LY, Hsieh WH, Ko PC, Liu YB, Lin C, Chang YC, Wang CY, Young VH, Chiang WC, Lin JL, Chen WJ, Ma MH. (2013) A New Method to Estimate The Amplitude Spectrum Analysis of Ventricular Fibrillation during Cardiopulmonary Resuscitation, Resuscitation
  35. Wu HT, Liu CC, Lo MT, Hsu PC, Liu AB, Chang KY, Tang CJ. (2013)  Multiscale Cross-Approximate Entropy Analysis As A Measure of Complexity Among The Aged and Diabetic, Comput Math Methods Med
  36. Wu HT, Hsu PC, Sun CK, Liu AB, Lin ZL, Tang CJ, Lo MT, (2013) Assessing Vascular Endothelial Function Using Frequency and Rank Order Statistics,  Physica A
  37. Wu HT, Hsu PC, Sun CK, Wang HJ, Liu CC, Chen HR, Liu AB, Tang CJ, Lo MT, (2013) Assessment of Autonomic Dysfunction in Patients with Type 2 Diabetes Using Reactive Hyperemia, J Theor Biol.
  38. Wu HT, Lo MT, Chen GH, Sun CK, Chen JJ. (2013) Novel Application of A Multiscale Entropy Index As A Sensitive Tool for Detecting Subtle Vascular Abnormalities in The Aged and Diabetic, Comput Math Methods Med.
  39. Lin YJ, Lo MT, Lin C, Chang SL, Lo LW, Hu YF, Chao TF, Li CH, Chang YC, Hsieh WH, Chung FP, Tsao HM, Chang HY, Huang NE, Chen SA, (2013) Nonlinear Analysis of Fibrillatory Electrograms Similarity to Optimize The Detection of Complex Fractionated Electrograms during Persistent Atrial Fibrillation, J Cardiovasc Electrophysiol.
  40. Yang AC, Huang CC, Liu ME, Liou YJ, Hong CJ, Lo MT, Huang NE, Peng CK, Lin CP, Tsai SJ, (2013) The APOE Ε4 Allele Affects Complexity and Functional Connectivity of Resting Brain Activity in Healthy Adults, Hum  Brain Mapp
  41. Lin YJ, Lo MT, Lin C, Chang SL, Lo LW, Hu YF, Hsieh WH, Chang HY, Lin WY, Chung FP, Liao JN, Chen YY, Hanafy D, Huang NE, Chen SA, (2013) The Role of Rotors in Maintaining Non-Paroxysmal Atrial Fibrillation: Insight from The Mapping and Catheter Ablation, Substrate Characteristics, and Prevalence, Circ Arrhythm Electrophysiol.




  1. Tsai PH, Lin C, Tsao J, Lin PF, Wang PC, Huang NE and Lo MT. (2012) Empirical Mode Decomposition based Detrended Sample Entropy in Electroencephalography for Alzheimer's disease, Journal of Neuroscience Methods
  2. Lin YJ, Suenari K, Lo MT, Lin C, Hsieh WH, Chang SL, Lo LW, Hu YF, Cheng CC, Lin WS, Kihara Y, Chao TF, Hartono B, Wu TJ, Huang NE and Chen SA. (2012) A Novel Assessment of the Temporal Variation in the Fractionated Electrograms Using a Histogram Analysis of the Local Fractionation Interval in Persistent Atrial Fibrillation Patients, Circulation:  Arrhythm Electrophysio (In press) 
  3. Hu K, Lo MT, Peng  C-K, Liu Y and Novak V. (2012) A nonlinear dynamic approach reveals a long-term stroke effect on cerebral blood flow regulation at multiple time scales, PLoS Computational Biology (in press ) 
  4. Wu XM, Lin YH, Chen, Hsu TP, Wu YW, Lin HJ, Hsu RB, Lee CM, Wang SS, Lo MT, Ho Y and Chen MF. (2012) Prognostic significance of adipocytokines in systolic heart failure patients, European Journal of Clinical Investigation (in press ) 
  5. Lin YH, Lin LY, Chen A, Wu XM, Lee JK, Su TC, Wu VC, Chueh SC, Lin WC, Lo MT, Wang PC, Ho YL and Wu KD. (2012) Adrenalectomy improves increased carotid intima-media thickness and arterial stiffness in patients with aldosterone producing adenoma, Atherosclerosis ,Vol. 221, Issue 1, 154–159
  6. Chang CH, Lee PL, Lo MT, Lee I, Yeh TK and Chang CY. (2012) Independence of amplitude-frequency and phase calibrations in an SSVEP-based BCI using stepping delay flickering sequences, IEEE Transactions on Neural System & Rehabiliattion Engineering  Vol.20, Issue 3, 305–312 
  7. Lin LY, Lo MT, Ko  P. CI, Chiang WC, Lin C, Hsiung KH, Lin JL, Chen WJ and Ma  M. HM. (2012) A new way to analyze resuscitation quality by reviewing automatic external defibrillator data, Resuscitation, Vol. 83, Issue 2, 171–176 
  8. Pan PJ, Tsai PH, Tsai CC, Chou CL, Lo MT and Chiu JH. (2012) Clinical Response and autonomic modulation as seen in heart rate variability in mechanical intermittent cervical traction: A pilot study: J Rehabil Med, Vol. 44, No.3, 229-234(6) 
  9. Liu D, Yang X, Wang G, Ma J, Liu Y, Peng C-K, Zhang J and Fang J. (2012) HHT based cardiopulmonary coupling analysis for sleep apnea detection, Sleep Medicine,13:503-509.
  10. Jiang  Bernard C, Yang WH, Shieh JS, Fan J. SZ and Peng C-K. (2011) Entropy-based method for COP data analysis, Theor Iss Ergonomics Sci , 1–20, iFirst
  11. Manor B, Hu K, Peng C-K, Lipsitz LA and Novak V. (2012) Posturo-respiratory synchronization: Effects of aging and stroke, Gait & Posture, Vol.36, issue 2, 254–259
  12. Yang AC, Huang CC, Yeh HL, Liu ME, Hong CJ, Tu PC, Tu JF, Huang NE, Peng C-K, Lin CP and Tsai SJ. (2012) Complexity of spontaneous BOLD activity in default mode network is correlated with cognitive function in normal male elderly: a multiscale entropy analysis, .Neurobiol Aging, (in press).
  13. Lin YH, Wu XM, Lee HH, Lee JK, Liu YC, Chang HW, Lin CY, Wu VC, Chueh SC, Lin LC, Lo MT, Ho YL and Wu KD, the TAIPAI study group. (2012) Adrenalectomy reverses myocardial fibrosis in patients with primary aldosteronism, J Hypertens, Jun 7. [Epub ahead of print]
  14. Huang WL, Lin YH,  Kuo  T. BJ, Chang LR, Chen YZ and Yang  C. CH. (2012) Methadone-mediated autonomic functioning of male patients with heroin dependence: the influence of borderline personality pattern, PLoS One, 7(5): e37464.
  15. Chang LR, Lin YH, Kuo T. BJ, Wu Chang HC, Liu CM, Liu CC, Hwu HG and Hwu C. CH. (2011) Autonomic Modulation and Health-related Quality of Life among Schizophrenic Patients Treated with Non-intensive Case Management, PLoS One, 6(11):e26378
  16. Hsieh IT, Yang C. CH, Chen CY, Lee GS, Kao FJ, Kuo KL and Kuo T. BJ. (2012) Uninterrupted wireless long-term recording of sleep patterns and autonomic function in freely moving rats, J. Med. Biol. Eng. (in press)
  17. Chen SP, Fuh JL, Lirng JF and Wang SJ. (2012) Hyperintense vessels on flair imaging in reversible cerebral vasoconstriction syndrome, Cephalalgia, 32(4) 271–278
  18. Peng KP, Fuh JL, Yuan HK, Shia BC and Wang SJ. (2011) New daily persistent headache: Should migrainous features be incorporated?, Cephalalgia,31(15) 1561–1569
  19. Liu CJ, Chang YS, Teng CJ, Chen TJ, Ou SM, Tzeng CH and Wang SJ. (2012) Risk of extrathymic cancer in patients with myasthenia gravis in Taiwan: a nationwide population-based study,  European Journal of Neurology, 19: 746–751
  20. Chen WT, Wang SJ, Fuh JL, Ko YC, Lee YC, Hämäläinen  M. S and Lin YY. (2012) Visual cortex excitability and plasticity associated with remission from chronic to episodic migraine, Cephalalgia, 32(7) 537–543
  21. Lee PL, Chang HC, Hsieh TY, Deng HT and Sun CW, A brain wave actuated small robot car using ensemble empirical mode decomposition – based approach, IEEE transactions on systems, man, and cybernetics – part A (In press)
  22. Lu CW, Czosnyka M, Shieh JS, Smielewska A, Pickard JD and Smielewski P. (2012) Complexity of intracranial pressure correlates with outcome after traumatic brain injury, Brain, 135(Pt 8):2399-408.
  23. Yeh JR, Lin TY, Chen Y, Sun WZ, Abbod  Maysam F and Shieh JS. (2012) Investigating Properties of the Cardiovascular System Using Innovative Analysis Algorithms Based on Ensemble EmpiricalMode Decomposition, Computational and Mathematical Methods in Medicine, Article ID 943431, 11 pages
  24. Lan JY, Yeh RG, Abbod  Maysam F, Fan SZ and Shieh JS. (2012) Review: Intelligent Modeling and Control in Anesthesia, Med. Biol. Eng., doi: 10.5405/jmbe.1014
  25. Fan SZ, Wei Q, Shi PF, Chen YJ, Liu Q and Shieh JS. (2012) A comparison of patients’ heart rate variability and blood flow variability during surgery based on the Hilbert-Huang Transform, Biomedical Signal Processing and Control ,7, 465-473
  26. Liu Q, Wei Q, Fan SZ, Lu CW and Lin TY. (2012) Abbod Maysam F and and Shieh JS, Adaptive Computation of Multiscale Entropy and Its Application in EEG Signals for Monitoring Depth of Anesthesia During Surgery, Entropy, 14, 978-992
  27. Chang YT, Lin J, Shieh JS and Abbod Maysam F. (2012) Optimization the Initial Weights of Artificial Neural Networks via Genetic Algorithm Applied to Hip Bone Fracture Prediction, Advances in Fuzzy Systems, Article ID 951247, 9 pages
  28. Cui X, Lin CW, Abbod  Maysam F, Liu Q and Shieh JS. (2012) Diffuse Large B-cell Lymphoma Classification Using Linguistic Analysis and Ensembled Artificial Neural Networks, Journal of the Taiwan Institute of Chemical Engineers, 43, 15–23
  29. Fan SZ, Yeh JR, Chen BC and Shieh JS. (2011) Comparison of EEG Approximate Entropy and Complexity Measures of Depth of Anaesthesia during Inhalational General Anaesthesia, Journal of Medical and Biological Engineering, 31(5): 359-366
  30. Su MC, Lai SC, Wang PC, Hsieh YZ and Lin SC. (2011) A SOMO-based approach to the operating room scheduling problem, Expert Systems with Applications, 38, 15447–15454
  31. Chen YH, Wu YW, Yang WS, Wang SS, Lee CM, Chou NK, Hsu RB, Lin YH, Lin MS, Ho YL and Chen MF. (2012) Relationship between Bone Mineral Density and Serum Osteoprotegerin in Patients with Chronic Heart Failure, PLoS ONE, Vol.7, Issue 8, e44242
  32. Lu KY, Hsu WT, Tung PC, Tseng CJ, Huang NE and Lin SL. (2012) Application of Using Steganography and Empirical Mode Decomposition in Communications Security,  Information-An International Interdisciplinary Journal, (in press)
  33. Lin PH, Chen RH, Lee CH, Chang Y, Chen CS and Chen WY (2011) Studies of the binding mechanism between aptamers and thrombin by circular dichroism, surface plasmon resonance and isothermal titration calorimery, Colloids Surf B Biointerfaces, 1;88(2):552-8
  34. Hu WP, Huang LY, Kuo TC, Hu WW, Chang Y, Chen CS, Chen HC and Chen WY. (2012) Optimization of DNA-directed immobilization on mixed oligo(ethylene glycol) monolayers for immunodetection, Analytical Biochemistry, 423, 26–35
  35. Lin SF, Wang CM, Ding TJ, Tsai YL, Yang TH, Chen WY and Chang JY. (2012) Sensitive metal layer assisted guided mode resonance biosensor with a spectrum inversed response and strong asymmetric resonance field distribution, Optics Express , Vol.20, Issue 13, 14584
  36. Tsao CW, Lin CH, Cheng YC, Chien CC, Chang CC and Chen WY. (2012) Nanostructured silicon surface modifications for as a selective matrix-free laser desorption/ionization mass spectrometry, Analyst, 137, 2643–2650
  37. Cheng YC, Chen KH, Wang JS, Hsu WL, Chien CC, Chen WY and Tsao CW. (2012) Rapid analysis of abused drugs using nanostructured silicon surface assisted laser desorption/ionization mass spectrometry, Analyst, 7;137(3):654-61
  38. Lin SF, Ding TJ, Liu JT, Lee CC, Yang TH, Chen WY and Chang JY. (2011)  A Guided Mode Resonance Aptasensor for Thrombin Detection, Sensors, 11, 8953-8965
  39. Lin SF, Wang CM, Tsai YL, Ding TJ, Yang TH, Chen WY, Yeh SF and Chang JY. (2012) A model for fast predicting and optimizing the sensitivity of surface-relief guided mode resonance sensors, Sensors and Actuators B: Chemical
  40. Lin YJ, Chang SL, Lo LW, Hu YF, Suenari K, Li CH, Chao TF, Chung FP, Liao JN, Hartono B, Tso HW, Tsao HM, Huang JL, Kao T and Chen SA. (2012) A Prospective, Randomized Comparison of Modified Pulmonary Vein Isolation Versus Conventional Pulmonary Vein Isolation in Patients with Paroxysmal Atrial Fibrillation, J Cardiovasc Electrophysiol
  41. Chang HY, Lin YJ, Lo LW, Chang SL, Hu YF, Li CH, Chao TF, Yin WH and Chen SA. (2012) Sinus node dysfunction in atrial fibrillation patients: the evidence of regional atrial substrate remodelling, Europace. 
  42. Huang JL, Lin YJ, Lee PC, Chang HY, Hartono B, Lo LW, Chang SL, Hu YF, Suenari K, Li CH, Chao TF, Kibos A, Ting CT and Chen SA. (2012) Right atrial substrate remodeling and atrioventricular node conduction properties in patients with paroxysmal atrial fibrillation, Int J Cardiol, 158(3):447-9 
  43. Tsai WC, Wang JH, Lin YJ, Tsao HM, Chang SL, Lo LW, Hu YF, Chang CJ, Tang WH ,Huang SY, Suenari K, Tuan TC and Chen SA. (2012) Consistency of the Automatic Algorithm in Detecting Complex Fractionated Electrograms using an Electroanatomical Navigation System, Pacing Clin Electrophysiol. 35(8):980-9. 
  44. Yuan Y and Huang NE. (2012) A Reappraisal of Ocean Wave Studies, Journal of Geophysical Research, Vol.117, C00J27, 21 pp.
  45. Wu YT, Shyu KK, Jao CW, Liao YL, Wang TY, Wu HM, Wang PS, Soong BW. (2012) Quantifying cerebellar atrophy in multiple system atrophy of the cerebellar type (MSA-C) using three-dimensional gyrification index analysis. Neuroimage. 61(1):1-9.
  46. Taiwan Aneurysm Registry (TAR): Multivariate analysis of 2-month, 1-year, and 2-year outcomes after endovascular and microsurgical treatment of ruptured aneurysms. Interventional Neuroradiology
  47. Wu XM, Lin YH, Chen A, Hsu TP, Wu YW, Lin HJ, Hsu RB, Lee CM, Wang SS, Lo MT, Ho YL, Chen MF. (2012) Prognostic significance of adipocytokines in systolic heart failure patients. Eur J Clin Invest. 42(10):1079-1086.
  48. Lee WJ, Tsai CF, Gauthier S, Wang SJ, Fuh JL. (2012) The association between cognitive impairment and neuropsychiatric symptoms in patients with Parkinson's disease dementia. Int Psychogeriatr, 24(12):1980-7.
  49. Tsai CF, Lee WJ, Wang SJ, Shia BC, Nasreddine Z., Fuh JL (2012) Psychometrics of the Montreal Cognitive Assessment (MoCA) and its subscales: validation of the Taiwanese version of the MoCA and an item response theory analysis. International Psychogeriatrics, Vol.24 (4), pp 651-658
  50. Yang AC, Tsai SJ, Yang CH, Shia BC, Fuh JL, Wang SJ, Peng CK, Huang NE. (2012) Suicide and media reporting: a longitudinal and spatial analysis. Soc Psychiatry Psychiatr Epidemiol.
  51. Yang AC, Yang CH, Hong CJ, Liou YJ, Shia BC, Peng CK, Huang NE, Tsai SJ. (2012) Effect of age, sex, index admission, and predominant polarity on the seasonality of acute admissions for bipolar disorder: a population-based study. Chronobiology International (in press)
  52. Chen WH, Chen HC, Yang YS, Huang CJ, Chan Hardy WH, Hu WP (2012) Improved DNA detection by utilizing electrically neutral DNA probe in field-effect transistor measurements as evidenced by surface plasmon resonance imaging. Biosensors and Bioelectronics 
  53. Lin PH, Tsai CW, Wu JW, Ruaan RC, Chen WY. (2012) Molecular dynamics simulation of the induced-fit binding process of DNA aptamer and L-argininamide. Biotechnol J. doi:10.1002/biot.201200003..
  54. Yang AC, Tsai SJ. (2012) Is mental illness complex? From behavior to brain. Prog Neuropsychopharmacol Biol Psychiatry. pii: S0278-5846(12)00253-9. doi: 10.1016/j.pnpbp.2012.09.015.
  55. Aoi MC, Hu K, Lo MT, Selim M, Olufsen MS, Novak V. (2012) Impaired cerebral autoregulation is associated with brain atrophy and worse functional status in chronic ischemic stroke. PLoS One. 2012;7(10):e46794.
  56. Wu CH, Lee PL, Shu CH, Yang CY, Lo MT, Chang CY, Hsieh JC (2012) Empirical Mode Decomposition-Based Approach for Intertrial Analysis of Olfactory Event-Related Potential Features Chemosensory Perception
  57. Yuan-Jang Jiang, Matthew Huei-Ming Ma, Wei-Zen Sun, Kuan-Wu Chang, Maysam F. Abbod, Jiann-Shing Shieh (2012) Ensembled neural networks applied to modeling survival rate for the patients with out-of-hospital cardiac arrest. Artificial Life and Robotics
  58. Wang PS, Chen HC, Wu HM, Lirng JF, Wu YT, et al. (2012) Association between Proton Magnetic Resonance Spectroscopy Measurements and CAG Repeat Number in Patients with Spinocerebellar Ataxias 2, 3, or 6. PLoS ONE 7(10): e47479. doi:10.1371/journal.pone.0047479
  59. Liao YL, Lu CF, Wu CT, Lee JD, Lee ST, Sun YN, Wu YT. (2012) Using three-dimensional multigrid-based snake and multiresolution image registration for reconstruction of cranial defect. Med Biol Eng Comput.
  60. Kuo TB, Chen CY, Hsu YC, Yang CC. (2012) Performance of the frequency domain indices with respect to sleep staging. Clin Neurophysiol, 123(7):1338-45
  61. Wong HF, Lee CW, Chen YL, Wu YM, Weng HH, Wang YH, Liu HM. (2012) Prospective Comparison of Angio-Seal versus Manual Compression for Hemostasis after Neurointerventional Procedures under Systemic Heparinization. AJNR Am J Neuroradiol.


  1. Chen CH, Lee HC, Ling Q, Chen HR, Ko YA, Tsou TS, Wang SC, Wu LC, Lee HC. (2011) An all-statistics, high-speed algorithm for the analysis of copy number variation in genomes. Nucleic Acids Research, 39(13):e89.
  2. Ho YL, Lin C, Lin YH, Lo MT. (2011) The prognostic value of non-linear analysis of heart rate variability in patients with congestive heart failure-a pilot study of multiscale entropy. PLoS ONE, 6(4):e18699.
  3. Chen CY, Yang CC, Lin YY, Kuo TB. (2011) Locomotion-induced hippocampal theta is independent of visual information in rats during movement through a pipe. Behavioural Brain Research, 216(2):699-704.
  4. Guo D, Peng C-K, Mietus JE, Liu Y, Wu HL, Sun RS, Thomas RJ. (2011) ECG-derived cardiopulmonary analysis of pediatric sleep-disordered breathing. Sleep Medicine, 12:384-389.
  5. Yang AC, Tsai SJ, Huang NE, Peng C-K. (2011) Association of Internet search trends with suicide death in Taipei City, Taiwan, 2004-2009. J Affect Disord , 132(1-2):179-184.
  6. Yang AC, Tsai SJ, Hong CJ, Wang C, Chen TJ, Liou YJ, Peng C-K. (2011) Clustering heart rate dynamics is associated with β-adrenergic receptor polymorphisms: analysis by information-based similarity index. PLoS ONE,  4;6(5):e19232.
  7. Wu HT, Hsu PC, Lin CF, Wang HJ, Sun CK, Liu AB, Lo MT, Tang CJ. (2011) Multiscale entropy analysis of pulse wave velocity for assessing atherosclerosis in the aged and diabetic.  IEEE Transactions on Biomedical Engineering, 58(10);2978-2981.
  8. Yang AC, Fuh JL, Huang NE, Shia BC, Peng C-K, Wang SJ. (2011) Temporal associations between weather and headache: analysis by empirical mode decomposition. PLoS ONE, 6:e14612.
  9. Cui XR, Abbod MF, Liu Q, Shieh JS, Chao TY, Hsieh CY, Yang YC. (2011) Ensembled artificial neural networks to predict the fitness score for body composition analysis. The Journal of Nutrition, Health & Aging,  15(5):341-348.
  10. Yeh JR, Lin CW, Shieh JS. (2011) An approach of multiscale complexity in texture analysis of lymphomas. IEEE Signal Processing Letters, 18(4):239-242.
  11. Liu Q, Cui X, Abbod MF, Huang SJ, Y.-Y. Han YY, Shieh JS. (2011) Brain death prediction based on ensembled artificial neural networks in neurosurgical intensive care unit. Journal of the Taiwan Institute of Chemical Engineers, 42(1):97-107.
  12. Yang AC, Tsai SJ, Huang NE. (2011) Decomposing the association of completed suicide with air pollution, weather, and unemployment data at different time scales. Journal of Affective Disorders, 129(1-3):275-281.
  13. Wu Z, Huang NE, Wallace JM, Smoliak BV, Chen X. (2011) On the time-varying trend in global-mean surface temperature. Climate Dynamics37(3-4):759-773.
  14. Huang NE, Chen X, Lo MT, Wu Z. (2011) On Hilbert Spectral Representation: A True Time-Frequency Representation for Nonlinear and Nonstationary Data. Advances in Adaptive Data Analysis, 3(1-2):63–93.
  15. Wu Z, Huang NE, Chen X. (2011) Some considerations on physical analysis of data. Advances in Adaptive Data Analysis, 3(1-2):95-113.
  16. Lin PH, Chen RH, Lee CH, Chang Y, Chen CS, Chen WY. (2011) Studies of the binding mechanism between aptamers and thrombin by circular dichroism, surface plasmon resonance and isothermal titration calorimetry. Colloids Surf B Biointerfaces. 88(2):552-558.
  17. Liu JT, Lin PS, Hsin YM, Tsai JZ, Chen WY. (2011) Surface plasmon resonance biosensor for microalbumin detection. Journal of the Taiwan Institute of Chemical Engineers, 42:696–700.
  18. Huang SY, Lin YJ, Tsao HM, Chang SL, Lo LW, Hu HF, Suenari K, Lin YK, Huang JH, Chen IC, Ko WC, Ong ET, Chen SA. (2011) The biatrial substrate properties in different types of paroxysmal atrial fibrillation. Heart Rhyth, 8(7):961-967.
  19. Yang AC, Tsai SJYang CH, Kuo CH, Chen TJ, Hong CJ. (2011) Reduced physiologic complexity is associated with poor sleep in patients with major depression and primary insomnia. Journal of Affective Disorders, 131(1-3):179-185.
  20. Yang AC, Yang CH, Hong CJ, Tsai SJ, Kuo CH, Peng C-K, Mietus JE, Goldberger AL, Thomas RJ. (2011) Sleep state instabilities in major depressive disorder: Detection and quantification with electrocardiogram-based cardiopulmonary coupling analysis. Psychophysiology, 48:285–291.
  21. Burykin A, Costa MD, Peng C-K, Goldberger AL, Buchman TG. (2011) Generating Signals with Multiscale Time Irreversibility: The Asymmetric Weierstrass Function. Complexity, 16:29-38. 
  22. Yeh JR, Sun WZ, Wen YR, Shieh JS. (2011) A Novel Continuous Visual Analog Scale Model Derived from Pain-relief Demand Index via Hilbert Huang Transform for Postoperative Pain. Journal of Medical and Biological Engineering, 31(3):169-176. 
  23. Lin SF, DingTJ, Liu JT, Lee CC, Yang TH, Chen WY, Chang JY. (2011) A guided mode resonance aptasensor for thrombin detection. Sensors, 11(9):8953-8965.
  24. Shieh JS, Chiou YR, Fan SZ. (2011) Developing a monitoring psychological stress Index system via photoplethysmography. The Sixteenth International Symposium on Artificial Life and Robotics (AROB 16th’11), Jan. 27~29, B-Con Plaza, Beppu, Oita, Japan, pp. 699-702.




  1. Liu HM. (2011) Hybrid CTA in the pre-interventional planning for treatment of intracranial DAVF. 11th WFITN Congress.
  2. Huang A, Liu HY, Lee CW, Liu HM. (2011) Quantifying Sound Characteristics by Using a Hilbert-Huang Transform Approach. The 3rd International Conference on Hilbert-Huang Transform:Theory and Applications.
  3. Lee CH, Chen GH, Wu HT, Lo MT, Sun CK, Tang CJ. (2011) Multiscale Entropy Indicates Vascular A bnormalities in the Aged. Proceedings of the 2011 International Conference on Machine Learning and Cybernetics, Guilin, 10-13 July, 2011.